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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPE
All Species:
12.42
Human Site:
S2389
Identified Species:
22.78
UniProt:
Q02224
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02224
NP_001804.2
2701
316415
S2389
K
I
R
E
L
E
N
S
L
H
E
A
K
E
S
Chimpanzee
Pan troglodytes
XP_001170168
2701
316707
S2389
K
I
R
E
L
E
N
S
L
H
E
A
K
E
S
Rhesus Macaque
Macaca mulatta
XP_001110512
2701
316828
S2389
K
I
R
E
L
E
N
S
L
H
E
A
K
E
S
Dog
Lupus familis
XP_852631
1216
141588
K923
Q
I
E
R
D
Q
L
K
S
D
I
Q
D
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6RT24
2474
286506
V2180
T
T
E
Q
L
S
E
V
Y
Q
T
L
T
A
S
Rat
Rattus norvegicus
Q7TSP2
1385
159522
T1092
Q
S
A
Q
E
E
L
T
K
K
E
A
L
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420670
2150
248600
L1857
V
N
E
A
G
K
N
L
R
E
K
D
D
K
I
Frog
Xenopus laevis
NP_001080954
2954
339950
N2561
K
M
L
E
N
E
L
N
L
V
K
D
D
A
M
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524993
2013
231091
G1720
T
K
D
M
L
E
S
G
N
E
E
L
K
E
Q
Honey Bee
Apis mellifera
XP_001121311
1418
164919
T1125
C
I
D
T
E
R
R
T
G
M
W
A
K
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781622
2537
290578
I2213
W
E
E
R
A
N
T
I
C
G
E
I
Q
E
K
Poplar Tree
Populus trichocarpa
XP_002308893
1247
142380
A954
I
S
R
N
E
S
L
A
S
E
L
E
A
L
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187629
1348
152938
C1055
E
K
K
E
L
E
S
C
R
L
E
C
V
T
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.7
37.8
N.A.
60.5
21.2
N.A.
N.A.
37.1
31
N.A.
N.A.
26.1
24.8
N.A.
25.5
Protein Similarity:
100
99.2
98
42
N.A.
75
35.7
N.A.
N.A.
55
52.2
N.A.
N.A.
45.6
37.8
N.A.
48.8
P-Site Identity:
100
100
100
6.6
N.A.
13.3
20
N.A.
N.A.
6.6
26.6
N.A.
N.A.
33.3
26.6
N.A.
13.3
P-Site Similarity:
100
100
100
20
N.A.
20
40
N.A.
N.A.
26.6
46.6
N.A.
N.A.
40
33.3
N.A.
20
Percent
Protein Identity:
23.9
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
34.6
N.A.
N.A.
37.6
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
0
8
0
0
0
39
8
16
0
% A
% Cys:
8
0
0
0
0
0
0
8
8
0
0
8
0
0
0
% C
% Asp:
0
0
16
0
8
0
0
0
0
8
0
16
24
0
0
% D
% Glu:
8
8
31
39
24
54
8
0
0
24
54
8
0
47
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
8
8
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
24
0
0
0
0
0
% H
% Ile:
8
39
0
0
0
0
0
8
0
0
8
8
0
8
8
% I
% Lys:
31
16
8
0
0
8
0
8
8
8
16
0
39
8
8
% K
% Leu:
0
0
8
0
47
0
31
8
31
8
8
16
8
8
16
% L
% Met:
0
8
0
8
0
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
0
8
0
8
8
8
31
8
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
16
0
0
16
0
8
0
0
0
8
0
8
8
0
16
% Q
% Arg:
0
0
31
16
0
8
8
0
16
0
0
0
0
0
0
% R
% Ser:
0
16
0
0
0
16
16
24
16
0
0
0
0
0
31
% S
% Thr:
16
8
0
8
0
0
8
16
0
0
8
0
8
16
8
% T
% Val:
8
0
0
0
0
0
0
8
0
8
0
0
8
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _